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Upvoted, but what TFA is claiming is that codine w/o acetaminophen is roughly as affective as the combination, which isn't addressed in that analysis.


http://www.ncbi.nlm.nih.gov/pubmed/19588335 "AUTHORS' CONCLUSIONS: Single dose oxycodone is an effective analgesic in acute postoperative pain at doses over 5 mg; oxycodone is two to three times stronger than codeine. Efficacy increases when combined with paracetamol. Oxycodone 10 mg plus paracetamol 650 mg provides good analgesia to half of those treated, comparable to commonly used non-steroidal anti-inflammatory drugs, with the benefit of longer duration of action."

"http://www.ncbi.nlm.nih.gov/pubmed/20393966 AUTHORS' CONCLUSIONS: Single dose codeine 60 mg provides good analgesia to few individuals, and does not compare favourably with commonly used alternatives such as paracetamol, NSAIDs and their combinations with codeine, especially after dental surgery; the large difference between dental and other surgery was unexpected. Higher doses were not evaluated."




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