And for most items that’s not too big of a deal. A returned textbook or toaster can be re-sold after it’s been opened without much fear that it’s been tampered with but I’m not sure the same can be said for a hard drive.
Or maybe it’s more like a bottle of medicine. Even if it’s exceedingly unlikely that it’s been tampered with I’m not going to risk it if the manufacturer’s seal is broken. It’s just not worth it.
Textbooks are actually a bad example, now that an awful lot of them have one-time codes linked to online materials (homework, etc.). Sure, the contents of the book may not be "used up", but that doesn't mean it's necessarily "good-as-new".
It seems to me kind of like underwear: once you buy it, you keep it and in the unlikely event you need to return the item it goes right in the trash.