No you don't have to do anything.

Let's say I have something like

  (s/def :thespec (s/or :foo ::foo 
                        :bar ::bar))

I can then use it in conjunction with core.match like

  (match [(s/conform :thespec val)]
    [:foo x] (do-something-with x)
    [:bar y] (do-something-else-with y))

Which imho is an easier way to navigate these things.