The health effects of high CO2 concentration start to appear in the mid-thousands of ppm. These problems are about an order of magnitude away from each other.
Yes, that's what the data suggests. It's just not what the question was...
Of course, the data is necessarily all about short term exposure, not non-stop. I'm inclined to think that it won't be too bad, if there is a direct effect at lower levels.
You can't use ventilation to bring the indoor CO2 concentration down to, say, 350ppm like it used to be outdoors.
But I think the answer is... practical, sure I guess. expensive? energy intensive? waste intensive? also yes.