For me a little disadvantage of Meson is that it is implemented in Python. With my interest in minimal systems and bootstrapping I would hope that it would get to be reimplemented in something easier to bootstrap or (maybe preferable) Python environment/version problems would get solved before the wider adoption. I understand, that it may not be as much a problem for others.
For what it is worth, there is Muon, a third-party implementation of Meson written in C99 [1].
Haven't used it myself yet, though Muon has been in steady development over the last few years, and the developers claim that they implement the vast majority of the Meson core features.
I was going to try replacing the KeePassXC build (which is one of the more complicated CMake builds I've had hand-to-hand with) to see what that experience would be like, but they report all the Qt flavors are unsupported: https://muon.build/releases/edge/docs/status.html
I'm aware I could just vanilla Meson but I was specifically interested in kicking the tires on the dbg in Muon since CLion just recently added debugging to CMake and I wanted to compare and contrast
This means muon can fairly easily implement user-defined functions without making the language Turing complete. If they did this I would happily (re)consider switching from CMake.