Subtle differences are not that easy to compare. You would have to test reading and comprehension speed and also while skimming and searching information.
If some font, color, or UI feature provides 1-5% improvement, it's huge because it accumulates over long term, but it's hard to notice immediately.
If some font, color, or UI feature provides 1-5% improvement, it's huge because it accumulates over long term, but it's hard to notice immediately.