I don't know about that. We didn't learn anything about cache lines while learning Scheme using The Structure and Interpretation of Computer Programs. Maybe that comes later?
1) My primary experience is with Common Lisp, not Scheme [1]
2) In any event, I wouldn't call someone whose total lisp experience is a SICP class a "lisp developer" and my introductory class in C didn't mention a cache line either (nor did we ever look at disassembly).
[1]: A quirk of the lisp community likely surprising to those who aren't involved is that whether or not Scheme is Lisp is debated. For the least flame-ish response by a prominent lisper, see https://groups.google.com/d/msg/comp.lang.lisp/Bj8Hx6mZEYI/6...